- "Why did our uncle leave on a journey when Cousin Ash needed him most? I mean, come on!"
- — Isaac Ketchum in Chapter 18
Isaac Ketchum is one of the main characters in The Miraculous Adventure of Tessa and Lunala. He is one of the twin sons of Ulysses and Stephanie Ketchum. His current Pokémon team consists of Zapdos and yellow core Minior (Lenalena).
- His voice actor, CJ Adams, is best known for playing Zach Wade in Against The Wild.